Route 61 is closed in both directions near Orwigsburg following a crash Friday afternoon.
The incident occurred just after 3:30 p.m. near the intersection of Route 61 and South Liberty Street in South Manheim Township.
According to initial reports, a truck rolled onto its side, blocking both lanes of traffic and forcing a full roadway closure.
Motorists are being detoured through Orwigsburg while crews work to clear the scene.
There is no word on injuries at this time.